GET THE APP

A General View on Gene Expressions

Commentary - Journal of Molecular Pathophysiology (2022)

A General View on Gene Expressions

Lucio Bogli*
 
Department of Neurosurgery, University Hospital St. Anna, Ferrara, Italy
 
*Corresponding Author:

Lucio Bogli, Department of Neurosurgery, University Hospital St. Anna, Ferrara, Italy, Email: Boglionee189@gmail.com

Received: 05-Jan-2022, Manuscript No. JMOLPAT-22-52169; Editor assigned: 07-Jan-2022, Pre QC No. JMOLPAT-22-52169 ; Reviewed: 21-Jan-2022, QC No. JMOLPAT-22-52169; Revised: 26-Jan-2022, Manuscript No. JMOLPAT-22-52169 ; Published: 02-Feb-2022

Description

Genetics is a branch of biology that studies genes, genetic diversity, and heredity in living things. In the twenty-first century, trait inheritance and molecular inheritance mechanisms of genes are still essential aspects of genetics, but modern genetics has evolved beyond inheritance to include the study of gene function and behaviour. The structure and function of genes, as well as their variation and distribution, are investigated in the context of the cell, the organism, and the population. Molecular genetics, epigenetics, and population genetics are only a few of the subfields of genetics. The organisms researched in this broad field come from all walks of life. Nature vs nurture refers to how genetic processes interact with an organism’s surroundings and experiences to determine development and behaviour. A living cell’s or organism’s intracellular or extracellular environment can turn gene transcription on or off. Two genetically identical maize seedlings, one in a temperate region and the other in an arid climate, are a famous example. While the average height of the two corn stalks may be genetically equivalent, due to a lack of water and nutrients in its surroundings, the one in the arid climate only grows to half the height of the one in the temperate zone. In genetics, there are three types of gene expression.

Genetic code

Genes typically exert their functional effect through causing the synthesis of proteins, which are complex molecules that perform the majority of the cell’s operations. Proteins are made up of one or more polypeptide chains, each of which has an amino acid sequence, and the DNA sequence of a gene is utilised to make a specific amino acid sequence. The transcription process begins with the creation of an RNA molecule with a sequence that matches the gene’s DNA sequence. Through a process known as translation, this messenger RNA molecule subsequently produces a corresponding amino acid sequence. Each codon, or three-nucleotide group in the sequence, correlates to one of the twenty potential amino acids in a protein or an instruction to end the amino acid sequence; this correspondence is referred to as the genetic code.

Nature and nurture

Although genes carry all of the information that an organism requires to function, the environment has a significant impact on the phenotypes that an organism shows. The effects of the human hereditary disorder phenylketonuria are heavily influenced by the environment. The phenylketonuria mutation interferes with the body’s capacity to break down the amino acid phenylalanine, resulting in a toxic build-up of an intermediate molecule, which leads to severe symptoms of increasing intellectual impairment and convulsions. However, people with the phenylketonuria mutation can live a normal and healthy life if they follow a rigorous diet that excludes this amino acid

Gene regulation

A particular organism’s genome has thousands of genes, yet not all of them must be active at any given time. When a gene is transcribed into mRNA, it is expressed, and there are various biological techniques for modulating gene expression so that proteins are made only when the cell need them. Transcription factors are DNA-binding regulatory proteins that either promote or inhibit gene transcription. Gene expression differences are notably noticeable in multicellular organisms, where cells all share the same genome but differ greatly in form and activity due to the expression of various sets of genes. A multicellular organism’s cells are all descended from a single cell that differentiates into multiple cell types in response to external and intercellular inputs, progressively establishing different gene expression patterns to produce different behaviours.

Copyright: © 2022 The Authors. This is an open access article under the terms of the Creative Commons Attribution NonCommercial ShareAlike 4.0 (https://creativecommons.org/licenses/by-nc-sa/4.0/). This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.